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N-Hydroxysuccinimide, 98+% - CAS 6066-82-6 - Formula C4H5NO3


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A10312
N-Hydroxysuccinimide, 98+%

CAS: 6066-82-6 MDL: MFCD00005516  EINECS: 228-001-3
Not regulated for shipping
Alternate Name: HOSu
1-Hydroxy-2,5-pyrrolidinedione

 

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Chemical Properties

Formula: C4H5NO3  Melting point: 94-99°
Formula weight: 115.09  Sensitivity: Hygroscopic

Literature References

Reagent for the preparation of active N-hydroxysuccinimide esters for peptide coupling with minimum racemization: J. Am. Chem. Soc., 86, 1839 (1964), or as an additive in the DCC method (see N,N'-Dicyclohexyl­carbodiimide, A10973) to suppress racemization: J. Am. Chem. Soc., 89, 7151 (1967). For peptide reagents, see Appendix 6.

For a study of the aminolysis of N-hydroxysuccinimide esters, see: J. Org. Chem., 53, 3583 (1988).


Other References

Beilstein: 113913
Harmonized Tariff Code:   2925.19

Risk & Safety

TSCA: Yes