|UN#:||UN2261||Hazard Class:||6.1||Packing Group:||II
||C8H10O || ||Boiling point:
||122.17 || ||Flash point:
O-Alkylation of this hindered phenol by alkyl halides has been achieved using NaOH with micellar catalysis by (1-Hexadecyl)trimethylammonium bromide, A15235: Tetrahedron, 44, 6677 (1988). Alkylation of the Li salt with MeI occurs preferentially on carbon to give the dimer of 2,6,6-trimethyl-2,4-cyclohexadienone: Org. Synth. Coll., 5, 1092 (1973).
Addition of lithiated 2,6-dimethylphenyl esters of alkanoic acids to carbonyl compounds has been used in a highly diastereoselective synthesis of ß-hydroxy acids. In some cases, only one of the two possible diastereomers is formed. For list of examples, see: Org. Synth. Coll., 7, 190 (1990).
|Harmonized Tariff Code:
GHS Hazard and Precautionary Statements
Hazard Statements : H301-H311-H314-H318-H411-H401
Toxic if swallowed. Toxic in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage. Toxic to aquatic life with long lasting effects. Toxic to aquatic life.
Precautionary Statements : P260-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501A
Do not breathe dust/fume/gas/mist/vapours/spray. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
Risk & Safety
|Toxic in contact with skin and if swallowed. Causes burns. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
|In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Avoid release to the environment. Refer to special instructions/Safety data sheets