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2-Bromothiazole, 99% - CAS 3034-53-5 - Formula C3H2BrNS

A14838 3034-53-5 2-Bromothiazole, 99% Alfa Aesar


Certificate of Analysis

2-Bromothiazole, 99%

CAS: 3034-53-5 MDL: MFCD00005316  EINECS: 221-229-4
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Pricing and Availability

Size ($) Price Your Price Quantity Options Availability
10g 52.30 Check Availability Add to Favorites Enter qty and click checkbox
25g 128.00 Check Availability Add to Favorites Enter qty and click checkbox
50g 219.00 Check Availability Add to Favorites Enter qty and click checkbox
250g 924.00 Check Availability Add to Favorites Enter qty and click checkbox

Chemical Properties

Formula: C3H2BrNS  Flash point: 63°(145°F)
Formula weight: 164.02  Density: 1.836
Boiling point: 171° Refractive Index: 1.5930

Literature References

2-Lithiothiazole can be obtained by direct lithiation of thiazole or, more conveniently, by exchange with 2-bromothiazole using n-BuLi: J. Org. Chem., 53, 1748 (1988). It behaves as a valuable formyl anion equivalent, and as such has been applied, mainly by Dondoni's group, in the syntheses of a variety of products; see, e.g.: Tetrahedron Lett., 34, 7319, 7323, 7327 (1993). See also 2-(Trimethyl­silyl)­thiazole, B21903. Reaction of 2-lithiothiazole with nitrones gives ɑ-aminoaldehydes: Tetrahedron Lett., 33, 4221 (1992); stereocontrolled addition to C-galacto-pyranosylnitrone has been used in syntheses of destomic acid, a component of the antibiotics destomycin and hygromycin, and of lincosamine, the sugar component of the anticancer antibiotic lincomycin: Synlett, 78 (1993). For applications of 2-lithiothiazole in the synthesis of the aza-sugar (+)-galactostsin, see: J. Org. Chem., 60, 4749 (1995). The Thiazole Aldehyde Synthesis has been reviewed by Dondoni: Synthesis, 1681 (1998).

Other References

Beilstein: 105724
Harmonized Tariff Code: 2934.10

GHS Hazard and Precautionary Statements

Hazard Statements : H315-H319-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Precautionary Statements : P210-P261-P280-P305+P351+P338-P405-P501A

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Harmful or Irritant

Risk & Safety

Risk Phrases: 36/37/38
Irritating to eyes, respiratory system and skin.
Safety Phrases: 26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable gloves.