4-Nitrobenzyl chloride, 99%
|UN#:||UN3261||Hazard Class:||8||Packing Group:||II
Pricing and Availability
||C7H6ClNO2 || ||Melting point:
||171.58 || |
Reagent for carboxyl protection in peptide synthesis. Derivatives are stable to HBr, but cleaved by hydrogenolysis: J. Am. Chem. Soc., 81, 5691 (1959); J. Chem. Soc., 4922 (1965). See also 4-Nitrobenzyl alcohol, A15742, 4-Nitrobenzyl bromide, A15236, and Appendix 6.
Has also been used for protection of the thiol group: J. Org. Chem., 37, 3550 (1972); J. Chem. Soc., Chem. Commun., 12 (1974).
|Harmonized Tariff Code:
GHS Hazard and Precautionary Statements
Hazard Statements : H301-H332-H314-H318-H341
Toxic if swallowed. Harmful if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Suspected of causing genetic defects.
Precautionary Statements : P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
Do not breathe dust/fume/gas/mist/vapours/spray. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
Risk & Safety
|Harmful by inhalation and if swallowed. Causes burns. Possible risk of irreversible effects
|In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).