1,4-Dithio-DL-threitol, 98%

CAS Number 3483-12-3 Synonyms
  • Cleland's Reagent DTT racemic
  • (±)-threo-1,4-Dimercapto-2,3-butanediol
Not regulated for shipping

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1,4-Dithio-DL-threitol, 98%

MDL: MFCD00004877
EINECS: 222-468-7

Chemical Properties

Formula: C4H10O2S2  Boiling point: 125-130°/12mm
Formula weight: 154.25  Flash point: >110°(230°F)
Melting point: 40-43° Sensitivity: Air Sensitive

Literature References

Protective agent for preventing oxidation of thiol groups and reagent for reduction of disulfide groups in proteins: Biochemistry, 3, 480 (1964); 11, 2939 (1972); J. Biol. Chem., 243, 716 (1968); Methods Enzymol., 25, 185 (1967); 143, 246 (1987).


Useful for stabilizing sulfhydryl-containing enzymes

GHS Hazard and Precautionary Statements

Hazard Statements : H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements : P261-P280-P305+P351+P338-P304+P340-P405-P501A

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Harmful or Irritant

Other References

Merck: 14,3376
Beilstein: 1719757
Harmonized Tariff Code: 2930.90
RTECS: EK1610000
1,4-Dithio-DL-threitol, 98% - CAS 3483-12-3 - Formula C4H10O2S2


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