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(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99% - CAS 20445-31-2 - Formula C10H9F3O3


Certificate of Analysis

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

CAS: 20445-31-2 MDL: MFCD00004184  EINECS: 243-829-5
Not regulated for shipping
Alternate Name: (+)-Mosher's acid


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Chemical Properties

Formula: C10H9F3O3  Density: 1.344
Formula weight: 234.18  Refractive Index: 1.4730
Melting point: 43-45° Optical Rotation: +72° (c=2 in methanol)
Boiling point: 105-107°/1mm Sensitivity: Hygroscopic
Flash point: >110°(230°F) 

Literature References

Widely used reagent for determination of optical purities of alcohols and amines by 1H or 19F NMR: J. Org. Chem., 34, 2453 (1969).

Other References

Merck: 14,6280
Beilstein: 2215440
Harmonized Tariff Code:   2918.99

GHS Hazard and Precautionary Statements

Hazard Statements : H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements : P261-P280-P305+P351+P338-P304+P340-P405-P501A

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Harmful or Irritant

Risk & Safety

Risk Phrases: 36/37/38
Irritating to eyes, respiratory system and skin.
Safety Phrases: 26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable gloves.