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498-02-2 - 4'-Hydroxy-3'-methoxyacetophenone, 98% - Acetovanillone - Apocynin - A10439 - Alfa Aesar

A10439 4'-Hydroxy-3'-methoxyacetophenone, 98%

CAS-Nummer
498-02-2
Synonyme
Acetovanillone
Apocynin

Größe Preis ($) Menge Verfügbarkeit
50g 30,69
250g 96,42
500g 155,20
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4'-Hydroxy-3'-methoxyacetophenone, 98%

MDL
MFCD00008747
EINECS
207-854-5

Chemische Eigenschaften

Formel
C9H10O3
Molmasse
166.18
Schmelzpunkt
112-116°
Siedepunkt
295-300°
Löslichkeit
Soluble in ethanol, chloroform, ether, hot water, benzene, ethyl acetate and dimethyl sulfoxide. Insoluble in petroleum ether.

Anwendungen

4'-Hydroxy-3'-methoxyacetophenone is used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is an enzyme responsible for reactive oxygen species production. It is also useful in the treatment of various inflammatory diseases and atherosclerosis. Further, it shows an anti-inflammatory activity and improves endothelial function by reducing oxidative stress. In addition to this, it is used for studying nitric oxide regulated processes in plants.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Harman-Ware, A. E.; Crocker, M.; Pace, R. B.; Placido, A.; Morton III, S.; DeBolt, S. Characterization of Endocarp Biomass and Extracted Lignin Using Pyrolysis and Spectroscopic Methods. Bioenergy Res. 2015, 8 (1), 350-368.

McKay, D. L.; Chen, C. Y. O.; Zampariello, C. A.; Blumberg, J. B. Flavonoids and phenolic acids from cranberry juice are bioavailable and bioactive in healthy older adults. Food Chem. 2015, 168, 233-240.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,741
Beilstein
637373
Harmonized Tariff Code
2914.50
TSCA
Yes
RTECS
AM8800000

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