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Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.
Zhang, Y.; Zhao, K. T.; Fox, S. G.; Kim, J.; Kirsch, D. R.; Ferrante, R. J.; Silverman, R. B. Tertiary amine pyrazolones and their salts as inhibitors of mutant superoxide dismutase 1-dependent protein aggregation for the treatment of amyotrophic lateral sclerosis. J. Med. Chem. 2015, 58 (15), 5942-5949.
Grzybowski, M., & Gryko, D. T. Diketopyrrolopyrroles: Synthesis, Reactivity, and Optical Properties. Adv. Opt. Mater. 2015, 3 (3), 280-320.
Gefahrenhinweise (EU): H226-H300-H310-H330
Flammable liquid and vapour. Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.