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Glutaraldehyde is used as a cross linking agent for gelatin, poly(vinyl alcohol) and polyheptapeptides. It is also used as a fixative for electron microscopy and as disinfectants. It provides water resistance to protein and polyhydroxy compounds by reacting through cross linking. It acts as an intermediate for the production of resins, dyestuffs, pharmaceuticals, photographic films and for stabilization of proteins on agarose beads, activation of polystyrene and glass for immobilization of antibodies and antigens and coupling peptides onto carrier proteins.
Woods, A.; Patela, A.; Spina, D.; Riffo-Vasquez, Y.; Babin-Morgan, A.; Rosales, R. T. M.; Sunassee, K.; Clark, S.; Collins, H.; Bruce, K.; Dailey, L. A.; Forbes, B. In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery. J. Controlled Release 2015, 210, 1-9.
Lu, W.; Ma, M.; Xu, H.; Zhang, B.; Cao, X.; Guo, Y. Gelatin nanofibers prepared by spiral-electrospinning and cross-linked by vapor and liquid-phase glutaraldehyde. Mater. Lett. 2015, 140, 1-4.
Gefahrenhinweise (EU): H301-H331-H314-H318-H334-H317
Toxic if swallowed. Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Do not breathe dusts or mists. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.