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Indole is used in perfumery and in preparing tryptophan, one of the 20 amino acids commonly found in animal proteins. It has important application in the industry of plant growth. It is used to prepare indoleacetic acid (auxin) and other plant growth substances which help the development of roots in plant. Indole and its derivatives are widely used in making perfumes, dyes, agrochemicals and medicines.
Tamotsu Horiuchi.; Hidetoshi Miura.; Kouichi Sumioka.; Satoshi Uchida. High Efficiency of Dye-Sensitized Solar Cells Based on Metal-Free Indoline Dyes. J. Am. Chem. Soc. 2004, 126, (39), 12218-12219.
Abdel-Rahmana, A.H.; Keshka, E.M.; Hannab, M.A.; Sh.M. El-Bady. Synthesis and evaluation of some new spiro indoline-based heterocycles as potentially active antimicrobial agents. Bioorganic & Medicinal Chemistry. 2004, 12, (9), 2483-2488.
2-Lithiation can be effected in a one-pot sequence via the Li carbamate: J. Chem. Soc., Perkin 1, 17, (1989); cf Indole, A14427.
Gefahrenhinweise (EU): H227-H302-H315-H319-H335
Combustible liquid. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.