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156-54-7 - Sodium butyrate, 98+% - Butyric acid sodium salt - A11079 - Alfa Aesar

A11079 Sodium butyrate, 98+%

CAS-Nummer
156-54-7
Synonyme
Butyric acid sodium salt

Größe Preis ($) Menge Verfügbarkeit
5g 17,20
100g 29,49
500g 93,70
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Sodium butyrate, 98+%

MDL
MFCD00002816
EINECS
205-857-6

Chemische Eigenschaften

Formel
C4H7NaO2
Molmasse
110.09
Schmelzpunkt
>300°
Sensitivität
Hygroscopic
Löslichkeit
Soluble in water, dimethyl sulfoxide and ethanol. Insoluble in ether.

Anwendungen

Decreases calcium release from intracellular stores. Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Further, it is used in the determination of the role of histone acetylation in chromatin structure and function.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Cavini, S.; Iraira, S.; Siurana, A.; Foskolos, A.; Ferret, A.; Calsamiglia, S. Effect of sodium butyrate administered in the concentrate on rumen development and productive performance of lambs in intensive production system during the suckling and the fattening periods. Small Rumin. Res. 2015, 123 (2-3), 212-217.

Xu, H.; McCoy, A.; Li, J.; Zhao, Y.; Ghishan, F. K. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. Am. J. Physiol. Gastrointest. Liver Physiol. 2015, 309 (6), G500-G505.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
3629439
Harmonized Tariff Code
2915.60
TSCA
Yes
RTECS
ET6400000

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