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56-45-1 - L-Serine, 99% - (S)-2-Amino-3-hydroxypropionic acid - H-Ser-OH - A11179 - Alfa Aesar

A11179 L-Serine, 99%

CAS-Nummer
56-45-1
Synonyme
(S)-2-Amino-3-hydroxypropionic acid
H-Ser-OH

Größe Preis ($) Menge Verfügbarkeit
25g 21,30
100g 67,70
500g 269,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

L-Serine, 99%

MDL
MFCD00064224
EINECS
200-274-3

Chemische Eigenschaften

Formel
C3H7NO3
Molmasse
105.09
Schmelzpunkt
214-224° dec.
Löslichkeit
Soluble in water. Insoluble in ethanol, ether and benzene.

Anwendungen

L-serine is used as a dietary supplement to improve health under certain conditions of malnutrition or physical stress, as a cosmetic incredient, as ingredients for cell culture media. It is used as a precursor to several amino acids, including glycine, cysteine and other metabolites such as sphingolipids and folate. It is used in bio-synthesis of purines and pyrimidines. It plays a vital role in catalytic function of enzymes. Further, L-serine and its metabolic products are essential for cell proliferation and specific functions of the central nervous system. .

Bemerkungen

Store in a cool place. Incompatible with strong oxidizing agents.

Literaturverweise

Has been used in a synthesis of D-amino acids. The configuration is inverted by conversion of the carboxyl group to the new alkyl chain by reaction with an organolithium reagent to give the ketone, which is deoxygenated by Raney nickel desulfurization of the thioketal, the hydroxymethyl group becoming the new carboxyl group by oxidation with oxygen over a Pt catalyst: J. Am. Chem. Soc., 106, 1095 (1984):

Sim, W. C.; Yin, H. Q.; Choi, H. S.; Choi, Y. J.; Kwak, H. C.; Kim, S. K.; Lee, B. H. l-Serine Supplementation Attenuates Alcoholic Fatty Liver by Enhancing Homocysteine Metabolism in Mice and Rats. J. Nutr. 2015, 145 (2), 260-267.

Zafarani-Moattar, M. T.; Asadzadeh, B. Effect of 1-carboxymethyl-3-methylimidazolium chloride,[HOOCMMIM][Cl], ionic liquid on volumetric, acoustic and transport behavior of aqueous solutions of l-serine and l-threonine at T= 298.15 K. J. Mol. Liq. 2015, 202, 79-85.

GHS Gefahren- und Sicherheitshinweise

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,8460
Beilstein
1721404
Harmonized Tariff Code
2922.50
TSCA
Yes
RTECS
VT8100000

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