A11467 4-Nitrocinnamaldehyde, predominantly trans, 98%
SDS
| Stock No. | Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|---|
| A11467-06 | 5g | 89,30 |
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| A11467-14 | 25g | 365,00 |
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| A11467-18 | 50g | 640,00 |
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4-Nitrocinnamaldehyde, predominantly trans, 98%
Chemische Eigenschaften
Anwendungen
Doebner-Miller reaction the 4- nitrocinnamaldehyde and 2-methylaniline in concentrated HC1 give the corresponding 8-methyl-2-phenylquinoline (3: R = 4'-N02) directly. The asymmetric Friedel-Crafts-type alkylation in aqueous media reaction of 4-Nitrocinnamaldehydr with N-methyl indole using trifluoroacetic acid (TFA) salt of the PEG-PS-supported prolyl peptide having the polyleucine tether as a catalyst. 4-Nitrocinnamaldehyde has been used in the preparation of 2, 2?-[(E)-3-(4-nitrophenyl) prop-2-ene-1,1-diyl] bis(3-hydroxy-5, 5-dimethylcyclohex-2-en-1-one).
Bemerkungen
Literaturverweise
Graham J. Atwell,; Bruce C. Baguley,; William A. Denny. Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as minimal DNA-intercalating antitumor agents with in vivo solid tumor activity . J. Med. Chem. 1989, 32(2),396-401.
Kengo Akagawa,; Takuhiro Yamashita,; Seiji Sakamoto,; Kazuaki Kudo. Friedel-Crafts-type alkylation in aqueous media using resin-supported peptide catalyst having polyleucine. Tetrahedron Letters. 2009, 50 (40) ,5602-5604.
GHS Gefahren- und Sicherheitshinweise
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Sicherheitshinweise: P280g-P305+P351+P338
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
