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89-73-6 - Salicylhydroxamic acid, 99% - 2-Hydroxybenzohydroxamic acid - A11528 - Alfa Aesar

A11528 Salicylhydroxamic acid, 99%

CAS-Nummer
89-73-6
Synonyme
2-Hydroxybenzohydroxamic acid

Größe Preis ($) Menge Verfügbarkeit
10g 25,20
25g 47,00
50g 82,70
100g 155,00
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Salicylhydroxamic acid, 99%

MDL
MFCD00002110
EINECS
201-934-3

Chemische Eigenschaften

Formel
C7H7NO3
Molmasse
153.14
Schmelzpunkt
ca 170° dec.
Löslichkeit
It is soluble in water.

Anwendungen

It is widely used for a variety of roles in biology and medicine as a chelating therapy. It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths. These compounds are used as extractants for the separation of valuable metals or minerals including copper, lead, gold, other rare earth metals and kaolin. Hydroxamic acids are also used to produce corresponding isocyanates by dehydration followed by rearrangement reaction. It is also used as a common ligand utilized in the synthesis of metallacrowns.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong bases. Stable under normal conditions.

Literaturverweise

Curt A. Davey & Roger E. Fenna. 2.3 Å Resolution X-ray Crystal Structure of the Bisubstrate Analogue Inhibitor Salicylhydroxamic Acid Bound to Human Myeloperoxidase:? A Model for a Prereaction Complex with Hydrogen Peroxide. Biochemistry. 1996, 35, (33), 10967-10973.

Mark L. Stolowitz.; Clarence Ahlem.; Karin A. Hughes.; Robert J. Kaiser.; Edward A. Kesicki.; Guisheng Li.; Kevin P. Lund.; Steven M. Torkelson.; and Jean P. Wiley. Phenylboronic Acid-Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization. Bioconjugate Chem. 2001, 12, (2), 229-239.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H303-H315-H319-H341-H335

May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. May cause respiratory irritation.

Sicherheitshinweise: P201-P261-P280-P305+P351+P338-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,8331
Beilstein
1210520
Harmonized Tariff Code
2928.00
TSCA
No
RTECS
VO6870000

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