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3-Amino-5-methyl-1H-pyrazole was employed as beta-sheet template to investigate its interaction with ferrocenoyl-dipeptides. It is also used in the synthesis of 4-aryl-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-ones. It can react with 4-Ethoxymethylene-2-phenyl-4H-oxazol-5-one to get N-(2-Methyl-7-oxo-4,7-dihydro-pyrazolo[1,5-a]pyrimidin-6-yl)-benzamide.
P Saweczko; G D Enright; H B Kraatz. Interaction of ferrocenoyl-dipeptides with 3-aminopyrazole derivatives: beta-sheet models? A synthetic, spectroscopic, structural, and electrochemical study. Inorganic Chemistry.2001, 40 (17), 4409-4419.
Wei Wang; Klaus Weisz. Characterization of peptide-pyrazole interactions in solution by low-temperature NMR studies. Chemistry: A European Journal.2007, 13 (3), 854-861.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
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