Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

563-41-7 - Semicarbazide hydrochloride, 99% - A11668 - Alfa Aesar

A11668 Semicarbazide hydrochloride, 99%

CAS-Nummer
563-41-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
100g 23,40
500g 67,90
2500g 263,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Semicarbazide hydrochloride, 99%

MDL
MFCD00013009
EINECS
209-247-0

Chemische Eigenschaften

Formel
CH4N3O•HCl
Molmasse
111.53
Schmelzpunkt
ca 176° dec.
Löslichkeit
Soluble in water (>100g/L).

Anwendungen

Semicarbazide hydrochloride is used as urease substrate and MAO inhibitor. Derivatizing agent for carbonyl compounds as their semicarbazones which produces crystalline compounds with characteristic melting points. Also used in heterocyclic synthesis. Semicarbazone formation has been used to separate carbonyl compounds from mixtures by adsorption onto silica gel from a hydrocarbon solution. Regeneration is by hydrolysis with oxalic acid.

Bemerkungen

Store in cool, dry conditions in well sealed container. Store away from oxidizing agent.

Literaturverweise

Phedias Diamandis et. al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nature Chemical Biology. 2007, 3 (5), 268-273.

Fumiko Marttila-Ichihara; Karolien Castermans; Kaisa Auvinen; Mirjam G A Oude Egbrink; Sirpa Jalkanen; Arjan W Griffioen; Marko Salmi. Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice. Journal of Immunology. 2010, 184 (6), 3164-3173.

Derivatizing agent for carbonyl compounds as their semicarbazones. Also used in heterocyclic synthesis. Semicarbazone formation has been used to separate carbonyl compounds from mixtures by adsorption onto silica gel from a hydrocarbon solution. Regeneration is by hydrolysis with oxalic acid: Tetrahedron, 37, 843 (1981).

Other reagents for the cleavage of semicarbazones include: Amberlyst® 15 in aqueous acetone: J .Chem. Soc., Perkin 1, 2563 (1988); Dowex® 50 in aqueous suspension: J. Org. Chem., 53, 878 (1988); CuSO4 in aqueous THF: J. Prakt. Chem., 322 1063 (1980).

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,8444
Beilstein
3593642
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2928.00
TSCA
Yes
RTECS
VT3500000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf