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(^+)-1,3-Butanediol acts as a co-monomer in the production of polyurethane and polyester resins. It is used as a humectant (to prevent loss of moisture) in cosmetics, especially in hair sprays and setting lotions. It is used in surfactants, inks, solvents for natural and synthetic flavorings. It is involved in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as euglycemic agents, which is used in the treatment of diabetes.
Kataoka, N.; Vangnai, A. S.; Pongtharangkul, T.; Tajima, T.; Yakushi, T.; Matsushita, K,; Kato, J. Construction of CoA-dependent 1-butanol synthetic pathway functions under aerobic conditions in Escherichia coli. J. Biotechnol. 2015, 204, 25-32.
Gregory, G. L.; Ulmann, M.; Buchard, A. Synthesis of 6-membered cyclic carbonates from 1,3-diols and low CO2 pressure: a novel mild strategy to replace phosgene reagents. RSC Adv. 2015, 5, 39404-39408.