I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Diethylamine is used as a corrosion inhibitor. It is also used in the production of rubber, resins, dyes and pharmaceuticals. It is also used to cook lysergic acid diethylamide (LSD) and is strictly watched by Drug Enforcement Administration (DEA).
Alkali metal diethylamides, generated with n-BuLi or NaH, have been used for the cleavage of ethers: J. Organomet. Chem., 55, 41 (1973); Synthesis, 638 (1980), and of alkyl aryl sulfides, for which HBr and HI are usually poor: Synthesis, 583 (1982).
In combination with Lithium aluminum hydride, A18116, generates lithium tris(diethylamino)aluminum hydride, which is a useful selective reducing agent, for example: esters to aldehydes: J. Org. Chem., 52, 5486 (1987); amides to aldehydes: Tetrahedron Lett., 32, 6903 (1991).
Wang, N. N.; Zhang, D. L.; Jiang, X. H. Detection of Xeljanz Enantiomers in Diethyl Amine Active Pharmaceutical Ingredients and Tablets. Chirality 2015, 27 (3), 235-238.
Higashino, T.; Soya, T.; Kim, W.; Kim, D.; Osuka, A. A Mobius Aromatic Hexaphyrin Bearing a Diethylamine Group: A Rigid but Smooth Conjugation Circuit. Angew. Chem. Int. Ed. 2015, 54 (18), 5456-5459.
Gefahrenhinweise (EU): H225-H302-H312-H332-H314
Highly flammable liquid and vapour. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes severe skin burns and eye damage.
Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.