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Reaction with triethyl orthoformate, catalyzed by sulfuric acid, to give the N-ethyl-N-formyl derivative (method as Org. Synth. Coll., 4, 420 (1963)), is the first step in a short and efficient strategy for the synthesis of the quinoline antibiotic norfloxacin: J. Chem. Soc., Chem. Commun., 1319 (1995)./n
Gefahrenhinweise (EU): H302-H311-H332-H315-H319-H373
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.
Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.