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Chloroacetone was used in the synthesis of double-chain nonionic surfactants with an acid decomposition function via acid-catalyzed condensation with fatty alcohols (octyl, decyl and dodecyl). It was also used in the synthesis of meso-tetramethyl tetrakis-(4-phenoxy acetone)calixpyrrole. It can also be used to make dye couplers for color photography and used in the Feist-Benary synthesis of furans.
Weijers CAGM, et al. Synthesis of optically pure 1, 2-epoxypropane by microbial asymmetric reduction of chloroacetone. Appl. Microbiol. Biotechnol.1992,38(3), 297-300.
He L, et al. L-Proline amide-catalyzed direct asymmetric aldol reaction of aldehydes with chloroacetone. Tetrahedron,2006, 62(2), 590-599.
Gefahrenhinweise (EU): H226-H301-H310-H330-H314-H318
Flammable liquid and vapour. Toxic if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor Dispose of contents/container in accordance with local/regional/national/international regulations.