I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
2,6-dimethylphenol is used in the synthesis of anti-oxidant compounds due to the phenol moiety in the structure. In addition, this compound is used as a reactant in the synthesis of polyphenylene ether polymers.
Yasar Thewalim; Fredrik Aldaeus; Anders Colmsjö. Retention time prediction of compounds in Grob standard mixture for apolar capillary columns in temperature-programmed gas chromatography. Analytical and Bioanalytical Chemistry.2009,393(1), 327-334.
Masahiro Ogata et. al. Antioxidant activity of propofol and related monomeric and dimeric compounds. Chemical & Pharmaceutical Bulletin,2005, 53(3), 344-346.
O-Alkylation of this hindered phenol by alkyl halides has been achieved using NaOH with micellar catalysis by (1-Hexadecyl)trimethylammonium bromide, A15235: Tetrahedron, 44, 6677 (1988). Alkylation of the Li salt with MeI occurs preferentially on carbon to give the dimer of 2,6,6-trimethyl-2,4-cyclohexadienone: Org. Synth. Coll., 5, 1092 (1973).
Addition of lithiated 2,6-dimethylphenyl esters of alkanoic acids to carbonyl compounds has been used in a highly diastereoselective synthesis of ß-hydroxy acids. In some cases, only one of the two possible diastereomers is formed. For list of examples, see: Org. Synth. Coll., 7, 190 (1990).
Gefahrenhinweise (EU): H301-H311-H314-H318
Toxic if swallowed. Toxic in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.
Do not breathe dusts or mists. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.