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4?-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
Dick B. Janssen. Substrate Specificity and Enantioselectivity of 4-Hydroxyacetophenone Monooxygenase. Appl. Environ. Microbiol. 2003, 69 (1),419-426.
W.B Gurnule.; P.K Rahangdale.; L.J Paliwal.; R.B Kharat. Synthesis, characterization and ion-exchange properties of 4-hydroxyacetophenone, biuret and formaldehyde terpolymer resins. React. Funct. Polym. 2003, 55 (3),255-265.
Gefahrenhinweise (EU): H301-H315-H319-H335
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.