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533-67-5 - 2-Deoxy-D-ribose, 99% - Thyminose - A11990 - Alfa Aesar

A11990 2-Deoxy-D-ribose, 99%

CAS-Nummer
533-67-5
Synonyme
Thyminose

Größe Preis ($) Menge Verfügbarkeit
1g 18,30
5g 64,10
25g 204,00
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2-Deoxy-D-ribose, 99%

MDL
MFCD00135904
EINECS
208-573-0

Chemische Eigenschaften

Formel
C5H10O4
Molmasse
134.13
Schmelzpunkt
76-85°
Sensitivität
Hygroscopic
Löslichkeit
Soluble in water.

Anwendungen

2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

Bemerkungen

Store in a cool place. Incompatible with strong oxidizing agents.

Literaturverweise

Starting material for a free-radical coupling reaction (employing homolytic fission of a derivative with 2-Mercaptopyridine N-oxide, A14152) which provides a facile preparative method for C-nucleosides: Chem. Lett., 1673 (1992).

Koh, G.; Yang, E. J.; Kim, J. Y.; Hyun, J.; Yoo, S.; Lee, S. A. Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2?deoxy?D?ribose?induced beta?cell damage. Mol. Med. Rep. 2015, 12 (4), 5314-5320.

Azofra, L. M.; Quesada-Moreno, M. M.; Alkorta, I.; Avilés-Moreno, J. R.; López-González, J. J.; Elguero, J. Carbohydrates in the gas phase: conformational preference of d-ribose and 2-deoxy-d-ribose. New J. Chem. 2014, 38 (2), 529-538.

GHS Gefahren- und Sicherheitshinweise

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2908
Beilstein
1721978
Harmonized Tariff Code
2940.00
TSCA
Yes
RTECS
SB7230000

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