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13139-17-8 - N-(Benzyloxycarbonyloxy)succinimide, 98% - Benzyl N-succinimidyl carbonate - Cbz-ONSu - A12153 - Alfa Aesar

A12153 N-(Benzyloxycarbonyloxy)succinimide, 98%

CAS-Nummer
13139-17-8
Synonyme
Benzyl N-succinimidyl carbonate
Cbz-ONSu

Größe Preis ($) Menge Verfügbarkeit
5g 14,94
25g 48,93
100g 123,30
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

N-(Benzyloxycarbonyloxy)succinimide, 98%

MDL
MFCD00005513
EINECS
236-075-3

Chemische Eigenschaften

Formel
C12H11NO5
Molmasse
249.23
Schmelzpunkt
77-82°
Sensitivität
Moisture Sensitive
Löslichkeit
Soluble in chloroform, methanol, acetone (0.1 g/mL).

Anwendungen

N-(N-Benzyloxycarbonyloxy)succinimide is a reagent used in the preparation of peptide thioacids view peptide precursors. Also used in the preparation of amino glycoside derivatives for the function of topoisomerase for both human and bacterial inhibition.

Bemerkungen

Moisture sensitive. Storage temperature 2-8°C. Store away from oxidizing agents, water/ moisture.

Literaturverweise

Hassan Ali Zamani. Erbium(III) PVC membrane sensor based on N-(benzyloxycarbonyloxy)succinimide as a new neutral ionophore. Chin. Chem. Lett. 2011, 22 (3), 346-349.

Selective reagent for the introduction of the benzyloxycarbonyl (Cbz or Z) protecting group, avoiding the formation of amino acid dimers: Tetrahedron Lett., 4765 (1966); J. Antibiot., 25, 695 (1972); 34, 513 (1981); Can. J. Chem., 60, 976 (1982).

Especially convenient for the selective protection of the -amino group of lysine and ornithine: Can. J. Chem., 54, 733 (1976); Rec. Trav. Chim., 99, 400 (1980). See Appendix 6.

Weitere Referenzen

Beilstein
1387927
Harmonized Tariff Code
2925.19
TSCA
No

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