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L-Leucine plays a vital role in hemoglobin formation, protein synthesis and metabolic functions. It assists the growth and repair of muscle and bone tissue. It is used in the treatment of amyotrophic lateral sclerosis - Lou Gehrig's disease. It prevents the breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. It is also used as a food additive and flavor enhancer. Further, it is used to preserve muscle glycogen.
Yang, Y.; Wu, Z.; Meininger, C. J.; Wu, G. l-Leucine and NO-mediated cardiovascular function. Amino Acids 2015, 47 (3), 435-447.
Gao, Y.; Childers, E. P.; Becker, M. L. l-Leucine-Based Poly(ester urea)s for Vascular Tissue Engineering. ACS Biomater. Sci. Eng. 2015, 1 (9), 795-804.