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Sodium chloroacetate is used to prepare dyes and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor.
A convenient method for the conversion of arylamines to the corresponding N,N-diacetic acids is by lithiation followed by reaction with sodium chloroacetate. For discussion and limitations, see: Synthesis, 548 (1989).
Ding, F.; Qian, X.; Zhang, Q.; Wu, H.; Liu, Y.; Xiao, L.; Deng, H.; Du, Y.; Shi, X. Electrochemically induced reversible formation of carboxymethyl chitin hydrogel and tunable protein release. New J. Chem. 2015, 39 (2), 1253-1259.
Zhang, A.; Cheng, L.; Hong, S.; Yang, C.; Lin, Y. Preparation of anti-fouling silicone elastomers by covalent immobilization of carboxybetaine. RSC Adv. 2015, 5 (107), 88456-88463.
Gefahrenhinweise (EU): H301-H315
Toxic if swallowed. Causes skin irritation.
Wear protective gloves. IF SWALLOWED: Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.