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504-24-5 - 4-Aminopyridine, 98% - Fampridine - 4-Pyridinamine - A12405 - Alfa Aesar

A12405 4-Aminopyridine, 98%

CAS-Nummer
504-24-5
Synonyme
Fampridine
4-Pyridinamine

Größe Preis ($) Menge Verfügbarkeit
50g 53,25
250g 186,10
1000g 566,40
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4-Aminopyridine, 98%

MDL
MFCD00006439
EINECS
207-987-9

Chemische Eigenschaften

Formel
C5H6N2
Molmasse
94.12
Schmelzpunkt
157-161°
Siedepunkt
273-274°
Flammpunkt
164°(327°F)
Dichte
1.26
Löslichkeit
Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.

Anwendungen

It is used as a research tool, in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis. In the laboratory, 4-AP is a useful pharmacological tool in studying various potassium conductances in physiology and biophysics. Spinal cord injury patients have also seen improvement with 4-AP therapy.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

H Bostock et. al.The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres. Journal of Physiology. 1981, 313 301-315.

Shun-ichi Yamaguchi,; Michael A. Rogawski.Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice . Epilepsy Research. 1992, 11(1), 9-16.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H311-H315-H319-H335-H411-H401

Fatal if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Toxic to aquatic life with long lasting effects. Toxic to aquatic life.

Sicherheitshinweise: P273-P280h-P270-P301+P310-P305+P351+P338-P302+P352

Avoid release to the environment. Wear protective gloves/clothing. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF ON SKIN: Wash with plenty of soap and water.

Weitere Referenzen

Merck
14,3933
Beilstein
105782
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
US1750000

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