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64-69-7 - Iodoacetic acid, 97+% - A12410 - Alfa Aesar

A12410 Iodoacetic acid, 97+%

CAS-Nummer
64-69-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
25g 49,50
100g 162,00
500g 647,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Iodoacetic acid, 97+%

MDL
MFCD00002685
EINECS
200-590-1

Chemische Eigenschaften

Formel
ICH2CO2H
Molmasse
185.95
Schmelzpunkt
79-82°
Siedepunkt
208° dec.
Sensitivität
Light Sensitive
Löslichkeit
Soluble in water, alcohol and ethanol. Slightly soluble in ether and chloroform.

Anwendungen

Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

Bemerkungen

Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, bases and strong reducing agents.

Literaturverweise

Shimada, T.; Kuyama, H.; Sato, T. A.; Tanaka, K. Development of iodoacetic acid-based cysteine mass tags: detection enhancement for cysteine-containing peptide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal. Biochem. 2012, 421 (2), 785-787.

Scott, P. A.; Kaplan, H. J.; Sandell, J. H. Anatomical evidence of photoreceptor degeneration induced by iodoacetic acid in the porcine eye. Exp Eye Res 2011, 93 (4), 513-527.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H314

Toxic if swallowed. Causes severe skin burns and eye damage.

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5025
Beilstein
1739079
Gefahrenklasse
8
Verpackungsgruppe
II
Harmonized Tariff Code
2915.90
TSCA
Yes
RTECS
AI3500000

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