Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

345909-35-5 - 4-Hydroxyquinoline-2-carboxylic acid hydrate, 98% - Kynurenic acid - A12602 - Alfa Aesar

A12602 4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%

CAS-Nummer
345909-35-5
Synonyme
Kynurenic acid

Größe Preis ($) Menge Verfügbarkeit
1g 19,28
5g 81,58
25g 354,32
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%

MDL
MFCD00006753
EINECS
207-751-5

Chemische Eigenschaften

Formel
C10H7NO3•xH2O
Molmasse
189.17(anhy)
Schmelzpunkt
ca 275° dec.
Löslichkeit
Soluble in hot ethanol and water. Insoluble in ether. 

Anwendungen

Broad spectrum excitatory amino acid antagonist4-Hydroxyquinoline-2-carboxylic acid hydrate is used as an intermediate in synthetic chemistry. It acts as an antiexcitotoxic and anticonvulsant. It finds application in certain neurobiological disorders therapy.

Bemerkungen

Incompatible with oxidizing agents.

Literaturverweise

Pesek, J.; Svoboda, J.; Sattler, M.; Bartram, S.; Boland, W. Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis. Org. Biomol. Chem. 2015, 13 (1), 178-184.

Tajti, J.; Majlath, Z.; Szok, D.; Csati, A.; Toldi, J.; Fulop, F.; Vecsei, L. Novel Kynurenic Acid Analogues in the Treatment of Migraine and Neurodegenerative Disorders: Preclinical Studies and Pharmaceutical Design. Curr. Pharm. Des. 2015, 21 (17), 2250-2258.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5327
Beilstein
147451
Harmonized Tariff Code
2933.49
TSCA
No
RTECS
VB2080000

Empfohlen

  • A10192

    Quinaldic acid, 98%
  • A12471

    Benzo[b]thiophene-2-carboxylic acid, 98%
  • A13316

    L-Citrulline, 98%
  • L12760

    2-Amino-4-hydroxyquinoline hydrate, 97%, water ca 10%
  • L15827

    12-Molybdophosphoric acid hydrate, Mo >47.5%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf