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Benzimidazole is a building block for making anthelmintic drugs like albendazole, mebendazole and triclabendazole and anti-ulcer drugs like pantoprazole, rabeprazole, lansoprazole and omeprazole. It is used in the preparation of pyrene derived benzimidazole linked polymers (BILPs), which are used for selective carbon dioxide separation applications due to their properties like porous materials, regenerability and sorbent selection parameters.
Chaudhry, U.; Redman, E. M.; Raman, M.; Gilleard, J. S. Genetic evidence for the spread of a benzimidazole resistance mutation across southern India from a single origin in the parasitic nematode Haemonchus contortus. Int J Parasitol 2015, 45 (11), 721-728.
Dam, C. S.; Henarejos, S. A. P.; Tsolakou, T.; Segato, C. A.; Gammelgaard, B.; Yellol, G. S.; Ruiz, J.; Lambert, I. H.; Sturup, S. In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) arene complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis. Metallomics 2015, 7 (5), 885-895.
Gefahrenhinweise (EU): H303
May be harmful if swallowed.