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62-50-0 - Ethyl methanesulfonate, 99% - Ethyl mesylate - Methanesulfonic acid ethyl ester - A12938 - Alfa Aesar

A12938 Ethyl methanesulfonate, 99%

CAS-Nummer
62-50-0
Synonyme
Ethyl mesylate
Methanesulfonic acid ethyl ester

Größe Preis ($) Menge Verfügbarkeit
5g 26,37
10g 46,69
50g 143,17
250g 516,60
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Ethyl methanesulfonate, 99%

MDL
MFCD00007559
EINECS
200-536-7

Chemische Eigenschaften

Formel
CH3SO3CH2CH3
Molmasse
124.16
Siedepunkt
85-86°/10mm
Flammpunkt
100°(212°F)
Dichte
1.170
Brechungsindex
1.4180
Sensitivität
Moisture Sensitive
Löslichkeit
Miscible with water.

Anwendungen

Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.

Bemerkungen

Special handling precautions required. View MSDS prior to purchase. MSDS available online at www.alfa.com.Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.

Literaturverweise

Hartwig, B.; James, G. V.; Konrad, K.; Schneeberger, K.; Turck, F. Fast isogenic mapping-by-sequencing of ethyl methanesulfonate-induced mutant bulks. Plant Physiol. 2012, 160 (2), 591-600.

Gunther, W. C.; Coffing, S. L.; Dickinson, D. A.; Engel, M. E.; Fiedler, R. D.; O'Lone, S. D.; Dobo, K. L. Evaluation of the Pig-a, micronucleus, and comet assay endpoints in a 28-day study with ethyl methanesulfonate. Environ Mol Mutagen 2014, 55 (6), 492-499.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H340-H351-H361-H302

May cause genetic defects. Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Harmful if swallowed.

Sicherheitshinweise: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3827
Beilstein
773969
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2904.10
TSCA
Yes
RTECS
PB2100000

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