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Ethyl 3-aminocrotonate, is used as an intermediate in organic synthesis. It is also used as an active ingredient in pharmaceutical synthesis and feed auxiliary agent. It is also used as an active pharmaceutical intermediate.
SA Monti. The Nentizescu Condensation of Ethyl 3-Aminocrotonate and 1, 4-Benzoquinone1. The Journal of Organic Chemistry. 196631 (8) , 2669-2672.
SE Kudaibergenov.; AG Didukh. Synthesis, characterization and stimuli-sensitive properties of novel linear and crosslinked polybetaines based on acrylic acid and ethyl 3-aminocrotonate. Macromolecular Symposia . 2004207 (1) , 153-172.
Reacts with quinones in the Nenitzescu synthesis of indoles. For a review, see: Org. React., 20, 337 (1973):
Gefahrenhinweise (EU): H314-H318-H335
Causes severe skin burns and eye damage. Causes serious eye damage. May cause respiratory irritation.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.