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63-74-1 - Sulfanilamide, 98% - 4-Aminobenzenesulfonamide - A13001 - Alfa Aesar

A13001 Sulfanilamide, 98%

CAS-Nummer
63-74-1
Synonyme
4-Aminobenzenesulfonamide

Größe Preis ($) Menge Verfügbarkeit
100g 22,45
500g 51,91
2500g 202,91
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Sulfanilamide, 98%

MDL
MFCD00007939
EINECS
200-563-4

Chemische Eigenschaften

Formel
C6H8N2O2S
Molmasse
172.21
Schmelzpunkt
163-168°
Dichte
1.08
Löslichkeit
Soluble in water, acetone, ethanol, glycerol, propylene glycol and hydrochloric acid. Insoluble in chloroform, ether, benzene and petroleum ether.

Anwendungen

Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Intermediate for preparation of 2,6-disubstituted anilines, by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid. See, e.g.: Org. Synth. Coll., 3, 262 (1955).

Yang, L.; Zhou, S.; Xiao, Y.; Tang, Y.; Xie, T. Sensitive simultaneous determination of three sulfanilamide artificial sweeters by capillary electrophoresis with on-line preconcentration and contactless conductivity detection. Food Chem. 2015, 188, 446-451.

Bhattacharya, A.; Sharma, M.; Gulati, A.; Joshi, R., Chanda, S. K.; Ahuja, P. S. Histochemical evaluation of catechins in PEG stressed transgenic tea plants using catechin-specific-diazotized sulfanilamide reagent. Biotech. Histochem. 2015, 90 (1), 45-54.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335-H303

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,8925
Beilstein
511852
Harmonized Tariff Code
2935.00
TSCA
Yes
RTECS
WO8400000

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