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Sarcosine ethyl ester hydrochloride, It is used as intermediate in the synthesis of antienzyme agents for toothpaste. Found to be a marker for prostate cancer bioagression. It can be used to produce N-methyl-N-nitroso-glycine ethyl ester. This reaction will need reagent NaNO2, and the menstruum H2O and aq. acetic acid.
SI Mizushima.; T Shimanouchi.; M Tsuboi. Near Infrared Spectra of Compounds with Two Peptide Bonds and the Configuration of a Polypeptide Chain. VI. Further Evidence of the Internal Hydrogen Bonding and an Estimation of its Energy. J. Am. Chem. Soc. 1957, 79 (20), 5357-5361.
LG Marzilli.; DA Buckingham. The stereochemistry of some cobalt (III) triethylenetetramine complexes of glycine andsarcosine. Inorganic Chemistry. 1967, 6 (5), 1042-1052.