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2-Methyl-1,4-naphthoquinone is a prothrombogenic compound and is used as a model quinone in cell culture and in vivo investigations. 2-Methyl-1,4-naphthoquinone is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. 2-Methyl-1,4-naphthoquinone can be used as an oxidative injury inducing agent.
A. L. Bacharach. 2 - Methyl - 1: 4 - Naphthoquinone. Br Med J. 1940, 1, (4123), 72.
David Ross.; Hjordis Thor.; Sten Orrenius.; Peter Moldeus. Interaction of menadione (2-methyl-1,4-naphthoquinone) with glutathione. Chemico-Biological Interactions. 1985, 55, 177-184.
Gefahrenhinweise (EU): H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.