A13724 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99%
SDS
| Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|
| 10g | 23,40 |
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| 50g | 85,40 |
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| 250g | 300,00 |
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2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99%
Chemische Eigenschaften
Anwendungen
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is an irreversible membrane-bound receptor antagonist. It is used in synthetic chemistry, discovery, process R&D. It also acts as coupling reagents.
Bemerkungen
Literaturverweise
Myung Ho Hyun; Moon Hee Kang; Sang Cheol Han. Use of 2-ethoxy-1-(ethoxycarbonyl)-1, 2-dihydroquinoline as a convenient reagent for the selective protection or derivatization of 2-hydroxycarboxylic acids. Tetrahedron Letters.1999, 40 3435-3438.
Hans-Gerhard Loffler / Friedhelm Schneider. Inhibition of Aminoacylase from Hog Kidney by 2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinoline.Biological Chemistry Hoppe-Seyler.1987, 368 481-486.
Reagent for peptide coupling. Reaction proceeds via the anhydride of the acid component: J. Am. Chem. Soc., 90, 823, 1651 (1968); Int. J. Pept. Prot. Res., 26, 493 (1985). See Appendix 6.
For activation of ɑ -hydroxy acids, see: Tetrahedron Lett, 40, 3435 (1999) . Also used for the mild esterification of alcohols, e.g. for introduction of the levulinate protecting group (see Levulinic acid, A10813): Tetrahedron Lett., 23, 2615 (1982). For a useful esterification technique applicable to primary, secondary and tertiary alcohols, see: J. Org. Chem., 60, 7072 (1995).
GHS Gefahren- und Sicherheitshinweise
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Sicherheitshinweise: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
