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15761-39-4 - N-Boc-L-proline, 99% - Boc-Pro-OH - N-(tert-Butoxycarbonyl)-L-proline - A13744 - Alfa Aesar

A13744 N-Boc-L-proline, 99%

CAS-Nummer
15761-39-4
Synonyme
Boc-Pro-OH
N-(tert-Butoxycarbonyl)-L-proline

Größe Preis ($) Menge Verfügbarkeit
5g 25,00
25g 71,40
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N-Boc-L-proline, 99%

MDL
MFCD00037324
EINECS
239-848-3

Chemische Eigenschaften

Formel
C10H17NO4
Molmasse
215.25
Schmelzpunkt
132-136°
Löslichkeit
Soluble in acetic acid.

Anwendungen

N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).

Bemerkungen

Moisture and light sensitive. Incompatible with strong oxidizing agents.

Literaturverweise

Sultane, P. R.; Mete, T. B.; Bhat, R. G. A convenient protocol for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups. Tetrahedron Lett. 2015, 56 (16), 2067-2070.

Wang, H.; Li, N.; Yan, Z.; Zhang, J.; Wan, X. Synthesis and properties of novel helical 3-vinylpyridine polymers containing proline moieties for asymmetric aldol reaction. RSC Adv. 2015, 5 (65), 52410-52419.

GHS Gefahren- und Sicherheitshinweise

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
15828
Harmonized Tariff Code
2933.99
TSCA
Yes

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