Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

765-69-5 - 2-Methylcyclopentane-1,3-dione, 98% - A13936 - Alfa Aesar

A13936 2-Methylcyclopentane-1,3-dione, 98%

CAS-Nummer
765-69-5
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 26,73
25g 115,20
100g 388,06
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

2-Methylcyclopentane-1,3-dione, 98%

MDL
MFCD00001406
EINECS
212-153-2

Chemische Eigenschaften

Formel
C6H8O2
Molmasse
112.13
Schmelzpunkt
212-216°
Löslichkeit
Solubility in hot Methanol (almost transparency).

Anwendungen

2-Methylcyclopentane-1,3-dione is an efficient synthon for the synthesis of (±)-α-cuparenone. The alkylation of 2-methylcyclopentane-1,3-dione (A) with 2-(1-naphthyl)ethyl bromide gives only the O-alkylation product. Mixtures of C- and O-alkyl derivatives are obtained. Michael addition of 2-methylcyclopentane-1,3-dione to methyl vinyl ketone in water gives 2-methyl-2-(3-oxo- butyl)-1,3-cyclopentanedione (3), an important intermediate of natural product chemistry. 2-Methylcyclopentane-1, 3-dione is an efficient synthon for the synthesis of (±)-α-cuparenone.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

Joseph P. John,; S. Swaminathan,; P. S. Venkataramani. 2-Methylcyclopentane-1,3-Dione. Organic Syntheses. year of publication , volume issue , pg no.

Victor J. Grenda,; Glenn W. Lindberg,; Norman L. Wendler,; Seemon H. Pines. A convenient synthesis of 2-methylcyclopentane-1,3-dione . J. Org. Chem. 1967, 32 (4), 1236-1237.

Valuable intermediate for steroid synthesis. For a review, see: Synthesis, 477 (1989). Condensation with methyl vinyl ketone and proline-catalyzed asymmetric aldol cyclization of the product gives a diketone useful in steroid and prostaglandin synthesis: Org. Synth. Coll., 7, 363 (1990):

Weitere Referenzen

Beilstein
1237255
Harmonized Tariff Code
2914.29
TSCA
No

Empfohlen

  • A11218

    2-Methylcyclohexane-1,3-dione, 98+%
  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • A12044

    Chloramine-T trihydrate, 98%
  • A14548

    Methyl carbazate, 98%
  • A15139

    Hexamethyldisilazane, 98+%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf