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695-34-1 - 2-Amino-4-methylpyridine, 98% - 2-Amino-4-picoline - 4-Methyl-2-pyridinamine - A14177 - Alfa Aesar

A14177 2-Amino-4-methylpyridine, 98%

CAS-Nummer
695-34-1
Synonyme
2-Amino-4-picoline
4-Methyl-2-pyridinamine

Größe Preis ($) Menge Verfügbarkeit
25g 16,56
100g 27,19
500g 94,40
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

2-Amino-4-methylpyridine, 98%

MDL
MFCD00006321
EINECS
211-780-9

Chemische Eigenschaften

Formel
C6H8N2
Molmasse
108.14
Schmelzpunkt
97-101°
Siedepunkt
231°
Flammpunkt
118°(244°F)
Sensitivität
Hygroscopic
Löslichkeit
Soluble in water (41 mg/ml at 20°C), lower alcohols (slightly), chloroform, ethyl acetate, and DMF.

Anwendungen

2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methyl­pyridinium 2-hy­droxy­benzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.

Bemerkungen

Hygroscopic. Incompatible with oxidizing agents and moisture. Store under dry inert gas. Protect from humidity and water. Store at -20°C.

Literaturverweise

Madhukar Hemamalini; Hoong-Kun Fun. 2-Amino-4-methyl-pyridinium 2-hy-droxy-benzoate. Acta Crystallographica Section E.2010, 66 (Pt 8), o2151-o2152.

W S Faraci; A A Nagel; K A Verdries; L A Vincent; H Xu; L E Nichols; J M Labasi; E D Salter; E R Pettipher. 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. British Journal of Pharmacology.1996, 119 (6), 1101-1108.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H311-H315-H335-H318

Toxic if swallowed. Toxic in contact with skin. Causes skin irritation. May cause respiratory irritation. Causes serious eye damage.

Sicherheitshinweise: P280-P305+P351+P338-P309-P310-P337+P313

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. If eye irritation persists: Get medical advice/attention.

Weitere Referenzen

Merck
14,466
Beilstein
107066
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
TJ5150000

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