Biotin is a form of vitamin B that helps the body to break down fats and carbohydrates. It is used as an alternative medicine to treat or prevent biotin deficiency, which is caused by malnutrition, rapid weight loss, long-term tube feeding and other medical conditions. It is an essential vitamin which is important for amino acid and energy metabolism.
Fraschetti, C.; Filippi, A.; Guarcini, L.; Steinmetz, V.; Speranza, M. Structure and Conformation of Protonated d-(+)-Biotin in the Unsolvated State. J. Phys. Chem. B 2015, 119 (20), 6198-6203.
Broussard, T. C.; Pakhomova, S.; Neau, D. B.; Bonnot, R.; Waldrop, G. L. Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry 2015, 54 (24), 3860-3870.