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372-19-0 - 3-Fluoroaniline, 98+% - A14228 - Alfa Aesar

A14228 3-Fluoroaniline, 98+%

CAS-Nummer
372-19-0
Synonyme

Größe Preis ($) Menge Verfügbarkeit
25g 42,00
100g 157,00
500g 629,00
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3-Fluoroaniline, 98+%

MDL
MFCD00007758
EINECS
206-747-0

Chemische Eigenschaften

Formel
C6H6FN
Molmasse
111.12
Siedepunkt
186-187°
Flammpunkt
77°(170°F)
Dichte
1.156
Brechungsindex
1.5440
Löslichkeit
Miscible with ethanol and ethyl ether. Slightly miscible with chloroform and water.

Anwendungen

3-Fluoroaniline is used in the preparation of acetic acid-(3-fluoro-anilide by reacting with acetic acid anhydride. Further, it serves as a reagent in the preparation of radamide analogs as Grp94 inhibitors, which has potential to be antitumor agents.

Bemerkungen

Incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents.

Literaturverweise

Zhou, Y.; Yuan, Y.; You, L.; Anslyn, E. V. Dynamic Aminal-Based TPA Ligands. Chem. Eur. J. 2015, 21 (22), 8207-8213.

Yashkina, E. A.; Yashkin, S. N.; Svetlov, D. A.; Gorshkov, V. V. Themodynamics of adsorption and patterns of the gas-chromatographic retention of cyclic amines on surfaces of graphitized thermal carbon black. Russ. J. Phys. Chem. A 2015, 89 (9), 1672-1682.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H227-H302-H312-H331-H315-H319-H373

Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.

Sicherheitshinweise: P210u-P260-P280-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
1305471
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2921.42
TSCA
No
RTECS
BY1400000

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