Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

5394-63-8 - 2,2,6-Trimethyl-1,3-dioxin-4-one, 94%, cont. up to ca 6% acetone - Diketene acetone adduct - 2,2,6-Trimethyl-1,3-dioxolenone - A14254 - Alfa Aesar

A14254 2,2,6-Trimethyl-1,3-dioxin-4-one, 94%, cont. up to ca 6% acetone

CAS-Nummer
5394-63-8
Synonyme
Diketene acetone adduct
2,2,6-Trimethyl-1,3-dioxolenone

Größe Preis ($) Menge Verfügbarkeit
25g 24,82
100g 74,57
500g 232,80
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

2,2,6-Trimethyl-1,3-dioxin-4-one, 94%, cont. up to ca 6% acetone

MDL
MFCD00040468
EINECS
226-403-3

Chemische Eigenschaften

Formel
C7H10O3
Molmasse
142.15
Schmelzpunkt
Siedepunkt
65-67°/2mm
Flammpunkt
14°(57°F)
Dichte
1.094
Brechungsindex
1.4610
Löslichkeit
Soluble in Chloroform, Methanol. Not miscible in water.

Anwendungen

2,2,6-Trimethyl-1,3-dioxin-4-one is used in the synthesis of dihydropyrimininones as picomolar sodium iodide symporter inhibitors. It is also used in the synthesis of resorcinol amide Hsp90 Inhibitor AT13387. It is used in the synthesis of acetylketene by flash pyrolysis.

Bemerkungen

Store at 4°C. Protect from heat. Store away from oxidizing agents.

Literaturverweise

David M. Birney; Xiaolian Xu; Sihyun Ham and Xiaomeng Huang. Chemoselectivity in the Reactions of Acetylketene and Acetimidoylketene:? Confirmation of Theoretical Predictions. J. Org. Chem.1997, 62 (21), 7114-7120.

Convenient alternative to diketene in many reactions, stable in the absence of base: J. Am. Chem. Soc., 75, 5400 (1953).

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H225-H315-H319-H335

Highly flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P210-P261-P280-P240-P303+P361+P353-P305+P351+P338-P304+P340-P362-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
2408
Gefahrenklasse
3
Verpackungsgruppe
II
Harmonized Tariff Code
2912.50
TSCA
No

Empfohlen

  • A11358

    o-Xylene, 99%
  • A11669

    1,4-Dibromobutane, 98+%
  • A12197

    6-Mercaptopurine monohydrate, 98%
  • 11186

    Yttrium(III) acetate tetrahydrate, REacton®, 99.99% (REO)
  • 45770

    Phenyllithium, typically 1.9M in di-n-butyl ether

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf