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461-89-2 - 6-Azauracil, 98% - 1,2,4-Triazine-3,5(2H,4H)-dione - A14389 - Alfa Aesar

A14389 6-Azauracil, 98%

CAS-Nummer
461-89-2
Synonyme
1,2,4-Triazine-3,5(2H,4H)-dione

Größe Preis ($) Menge Verfügbarkeit
5g 48,20
25g 184,77
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6-Azauracil, 98%

MDL
MFCD00006456
EINECS
207-318-0

Chemische Eigenschaften

Formel
C3H3N3O2
Molmasse
113.08
Schmelzpunkt
274-282°
Löslichkeit
Partly soluble in water, ethanol, DMSO, and 1 M NH4OH (50 mg/ml).

Anwendungen

6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. 6-Azauracil has been widely used in investigations on modulation of transcription, especially in yeast models.

Bemerkungen

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literaturverweise

Françoise Exinger and François Lacroute. 6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae.Current Genetics.,1992,22(1), 9-11.

J. Škoda.; V. F. Hess and F. Šorm. Production of 6-azauracil riboside by Escherichia coli growing in the presence of 6-azauracil.Collect. Czech. Chem. Commun.,1957,22(4), 1330-1333.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
116472
Harmonized Tariff Code
2933.69
TSCA
Yes
RTECS
XY7700000

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