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4-Nitrotoluene is used as a basic chemical in the chemical industry for the manufacturing of intermediates.
Michán C, et al. In vivo construction of a hybrid pathway for metabolism of 4-nitrotoluene in Pseudomonas fluorescens.J. Bacteriol.,1997,179(9), 3036-3038.
Ju KS, et al. Evolution of a new bacterial pathway for 4-nitrotoluene degradation.Mol. Microbiol.,2011,82(2), 355-364.
In the presence of KOH, an unusual aerobic oxidation gives 4,4'-dinitrobibenzyl: Org. Synth. Coll., 4, 367 (1963). CrO3 in acetic anhydride gives the diacetate of 4-nitro-benzaldehyde: Org. Synth. Coll., 4, 713 (1963).
Gefahrenhinweise (EU): H301-H311-H331-H373
Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. May cause damage to organs through prolonged or repeated exposure.
Avoid release to the environment. Wear protective gloves. IF exposed or if you feel unwell: IF ON SKIN: