I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1,2-Cyclohexanedione is utilized as a substrate to study enzyme cyclohexane-1,2-dione hydrolase, which is a new tool to degrade alicyclic compounds. It also acts as a specific reagent for arginine residues.
Protection of trans-1,2-diols as cyclic diacetals has been accomplished by Ley's group using the diketone in combination with trimethyl orthoformate and camphorsulfonic acid. The method is particularly applicable to the carbohydrate field: Synlett, 793 (1996):
See also Org. Synth., 75, 170 (1997), for an alternative method.
Undergoes copper-catalyzed oxidative cleavage to give 2-halo diacids: Synthesis, 917 (1992):
Kawade, M.; Saha, A.; Upadhyaya, H. P.; Kumar, A.; Naik, P. D. Photodissociation Dynamics of Enolic 1,2-Cyclohexanedione at 266, 248, and 193 nm: Mechanism and Nascent State Product Distribution of OH. J. Phys. Chem. A. 2013, 117 (12), 2415-2426.
Pejlovas, A. M.; Barfield, M.; Kukolich. S. G. Microwave spectrum and molecular structure parameters for the 1,2-cyclohexanedione (monoenolic)-formic acid dimer. Chem. Phys. Lett. 2013, 613, 86-89.