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Bromoacetic acid is used in organic synthesis and as an alkylating agent. It is also used as a biochemical for proteomics research. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, dyes and agrochemicals.
E.A. Barnard.; W.D. Stein. The histidine residue in the active centre of ribonuclease: I. A specific reaction with bromoacetic acid. Journal of Molecular Biology. 1959, 1 (4-5), 339-349.
Philip J. Elving.; Isadore Rosenthal.; Marilyn Koll Kramer. Polarographic Behavior of Organic Compounds. IX. Iodoacetic Acid and the Bromoacetic Acids. J. Am. Chem. Soc. 1951, 73 (4), 1717-1722.
Reaction with a dialkyl phosphite followed by an aldehyde has been used in a convenient one-pot synthesis of acrylic acids: J. Org. Chem., 46, 2514 (1981). For examples with reaction schemes, see Chloroacetic acid, A11482 and 2-Bromopropionic acid, A17569.
Gefahrenhinweise (EU): H300-H310-H331-H314-H317
Fatal if swallowed. Fatal in contact with skin. Toxic if inhaled. Causes severe skin burns and eye damage. May cause an allergic skin reaction.
Do not breathe dusts or mists. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.