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2,4,6-Trimethylbenzoyl chloride is used, in the presence of pyridine, to protect OH groups as mesitoate esters.
Greg A. Urove.; Dennis G. Peters. Electrochemical reduction of 2,4,6-trimethylbenzoyl chloride and 2,4,6-trimethylbenzaldehyde at carbon and mercury cathodes in acetonitrile. Electrochimica Acta. 1994, 39 (10), 1441-1450.
Thomas H. Jukes. PANTOTHENIC ACID AND THE FILTRATE (CHICK ANTI-DERMATITIS) FACTOR. J. Am. Chem. Soc. 1939, 61 (4), 975-976.
Has been used, in the presence of pyridine, to protect OH groups as mesitoate esters, very stable to base hydrolysis: J. Am. Chem. Soc., 91, 4318 (1969). The group can be removed reductively, e.g. with LiAlH4: J. Chem. Soc. (C), 2944 (1971), or AlH3: J. Org. Chem., 57, 3431 (1992).
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.