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N-(4-Bromobutyl)phthalimide is used in organic synthesis and the production of pharmaceutical. It can react with 1-phenyl-piperazine to get N-[4-(4-phenyl-piperazin-1-yl)-butyl]-phthalimide. It is a useful synthesis reagent used to synthesize B-cyclodextrin derivatives.
S. Tomasi; M. Le Roch; J. Renault; J. C. Corbel and P. Uriac. N-alkylation of N1-mesitylenesulphonylputrescine with N-(4-bromobutyl)phthalimide: A Parallel Approach Using Multipin Solid-phase Synthesis. Pharmacy and Pharmacology Communications. 2000, 6 (4), 155-159.
Richard A. Glennon; Noreen A. Naiman; M. Edward Pierson; J. Doyle Smith; Abd M. Ismaiel; Milt Titeler; Robert A. Lyon. N-(phthalimidoalkyl) derivatives of serotonergic agents: a common interaction at 5-HT1A serotonin binding sites?. J. Med. Chem. 1989, 32 (8), 1921-1926.
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