1,1,1-Trifluoro-2,4-pentanedione has been used as reagent in the preparation of 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives.
Belen Zarranz; Andres Jaso; Ignacio Aldana; Antonio Monge. Synthesis and anticancer activity evaluation of new 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethyl-quinoxaline 1,4-di-N-oxide derivatives. Bioorganic & Medicinal Chemistry. 2004, 12, (13),3711-3721
Mansoureh Zahedi-Tabrizi; Fariba Tayyari; Zainab Moosavi-Tekyeh; Alireza Jalali; Sayyed Faramarz Tayyari. Structure and vibrational assignment of the enol form of 1,1,1-trifluoro-2,4-pentanedione. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2006, 65, (2),387-396
Chelating ligand. Review of chemistry of fluorinated ß-diketones: Russ. Chem. Rev., 50, 180 (1981).
For use in the preparation of trifluoromethyl pyrimidines by reaction with guanidines, see: Synth. Commun., 20, 913 (1990):
Gefahrenhinweise (EU): H226-H302-H315-H319-H335
Flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.