Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

144-48-9 - 2-Iodoacetamide, 98%, stab. with ca 5-8% water - A14715 - Alfa Aesar

A14715 2-Iodoacetamide, 98%, stab. with ca 5-8% water

CAS-Nummer
144-48-9
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 21,45
25g 63,12
100g 204,97
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

2-Iodoacetamide, 98%, stab. with ca 5-8% water

MDL
MFCD00008028
EINECS
205-630-1

Chemische Eigenschaften

Formel
ICH2CONH2
Molmasse
184.96
Schmelzpunkt
92-95°(dried)
Sensitivität
Light Sensitive
Löslichkeit
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

Anwendungen

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Bemerkungen

Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.

Literaturverweise

Zbancioc, G.; Mangalagiu, I. I.; Moldoveanu, C. Ultrasound assisted synthesis of imidazolium salts: An efficient way to ionic liquids. Ultrason. Sonochem. 2015, 23, 376-384.

Moriyama, M.; Metzger, S.; van der Vlies, A. J.; Uyama, H.; Ehrbar, M.; Hasegawa, U. Inhibition of Angiogenesis by Antioxidant Micelles. Adv. Healthcare Mater. 2013, 4 (4), 569-575.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H315-H319-H317-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
1739080
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2924.19
TSCA
Yes
RTECS
AC4200000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf